Strange India All Strange Things About India and world


  • Frye, M., Harada, B. T., Behm, M. & He, C. RNA modifications modulate gene expression during development. Science 361, 1346–1349 (2018).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Wiener, D. & Schwartz, S. The epitranscriptome beyond m6A. Nat. Rev. Genet. 22, 119–131 (2021).

    Article 
    CAS 

    Google Scholar 

  • Pan, T. Modifications and functional genomics of human transfer RNA. Cell Res. 28, 395–404 (2018).

    Article 
    CAS 

    Google Scholar 

  • Suzuki, T. The expanding world of tRNA modifications and their disease relevance. Nat. Rev. Mol. Cell Biol. 22, 375–392 (2021).

    Article 
    CAS 

    Google Scholar 

  • Alexandrov, A., Martzen, M. R. & Phizicky, E. M. Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. RNA 8, 1253–1266 (2002).

    Article 
    CAS 

    Google Scholar 

  • Alexandrov, A. et al. Rapid tRNA decay can result from lack of nonessential modifications. Mol. Cell 21, 87–96 (2006).

    Article 
    CAS 

    Google Scholar 

  • Filonava, L., Torres, A. G. & Ribas de Pouplana, L. A novel cause for primordial dwarfism revealed: defective tRNA modification. Genome Biol. 16, 216 (2015).

    Article 

    Google Scholar 

  • Shaheen, R. et al. Mutation in WDR4 impairs tRNA m7G46 methylation and causes a distinct form of microcephalic primordial dwarfism. Genome Biol. 16, 210 (2015).

    Article 

    Google Scholar 

  • Trimouille, A. et al. Further delineation of the phenotype caused by biallelic variants in the WDR4 gene. Clin. Genet. 93, 374–377 (2018).

    Article 
    CAS 

    Google Scholar 

  • Chen, X. et al. Speech and language delay in a patient with WDR4 mutations. Eur. J. Med. Genet. 61, 468–472 (2018).

    Article 

    Google Scholar 

  • Orellana, E. A. et al. METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation. Mol. Cell 81, 3323–3338.e14 (2021).

    Article 
    CAS 

    Google Scholar 

  • Dai, Z. et al. N7-methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression. Mol. Cell 81, 3339–3355.e8 (2021).

    Article 
    CAS 

    Google Scholar 

  • Ying, X. et al. METTL1-m7G-EGFR/EFEMP1 axis promotes the bladder cancer development. Clin. Transl. Med. 11, e675 (2021).

    Article 
    CAS 

    Google Scholar 

  • Han, H. et al. N7-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis. Nat. Commun. 13, 1478 (2022).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Chen, Z. et al. METTL1 promotes hepatocarcinogenesis via m7G tRNA modification-dependent translation control. Clin. Transl. Med. 11, e661 (2021).

    Article 
    CAS 

    Google Scholar 

  • Chen, J. et al. Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression. Cancer Commun. 42, 223–244 (2022).

    Article 

    Google Scholar 

  • Wang, C. et al. Methyltransferase-like 1 regulates lung adenocarcinoma A549 cell proliferation and autophagy via the AKT/mTORC1 signaling pathway. Oncol. Lett. 21, 330 (2021).

    Article 
    CAS 

    Google Scholar 

  • Ma, J. et al. METTL1/WDR4-mediated m7G tRNA modifications and m7G codon usage promote mRNA translation and lung cancer progression. Mol. Ther. 29, 3422–3435 (2021).

    Article 
    CAS 

    Google Scholar 

  • Liu, Y. et al. Overexpressed methyltransferase-like 1 (METTL1) increased chemosensitivity of colon cancer cells to cisplatin by regulating miR-149-3p/S100A4/p53 axis. Aging 11, 12328–12344 (2019).

    Article 
    CAS 

    Google Scholar 

  • Tian, Q. H. et al. METTL1 overexpression is correlated with poor prognosis and promotes hepatocellular carcinoma via PTEN. J. Mol. Med. 97, 1535–1545 (2019).

    Article 
    CAS 

    Google Scholar 

  • Chen, B. et al. N7-methylguanosine tRNA modification promotes tumorigenesis and chemoresistance through WNT/β-catenin pathway in nasopharyngeal carcinoma. Oncogene 41, 2239–2253 (2022).

    Article 
    CAS 

    Google Scholar 

  • Luo, Y. et al. The potential role of N7-methylguanosine (m7G) in cancer. J. Hematol. Oncol. 15, 63 (2022).

    Article 
    CAS 

    Google Scholar 

  • Suzuki, T. in Fine-Tuning of RNA Functions by Modification and Editing (ed. Grosjean, H.) 23–69 (Springer, 2005).

  • Motorin, Y. & Helm, M. tRNA stabilization by modified nucleotides. Biochemistry 49, 4934–4944 (2010).

    Article 
    CAS 

    Google Scholar 

  • Lorenz, C., Lunse, C. E. & Morl, M. tRNA modifications: impact on structure and thermal adaptation. Biomolecules 7, 35 (2017).

    Article 

    Google Scholar 

  • Ohira, T. et al. Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance. Nature 605, 372–379 (2022).

    Article 
    ADS 
    CAS 

    Google Scholar 

  • Jonkhout, N. et al. The RNA modification landscape in human disease. RNA 23, 1754–1769 (2017).

    Article 
    CAS 

    Google Scholar 

  • Kirchner, S. & Ignatova, Z. Emerging roles of tRNA in adaptive translation, signalling dynamics and disease. Nat. Rev. Genet. 16, 98–112 (2015).

    Article 
    CAS 

    Google Scholar 

  • Boccaletto, P. et al. MODOMICS: a database of RNA modification pathways. 2021 Update. Nucleic Acids Res. 50, D231–D235 (2022).

    Article 
    CAS 

    Google Scholar 

  • Juhling, F. et al. tRNAdb 2009: compilation of tRNA sequences and tRNA genes. Nucleic Acids Res. 37, D159–D162 (2009).

    Article 

    Google Scholar 

  • Alexandrov, A., Grayhack, E. J. & Phizicky, E. M. tRNA m7G methyltransferase Trm8p/Trm82p: evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p. RNA 11, 821–830 (2005).

    Article 
    CAS 

    Google Scholar 

  • Wu, J., Hou, J. H. & Hsieh, T. S. A new Drosophila gene wh (wuho) with WD40 repeats is essential for spermatogenesis and has maximal expression in hub cells. Dev. Biol. 296, 219–230 (2006).

    Article 
    CAS 

    Google Scholar 

  • Lin, S. et al. Mettl1/Wdr4-mediated m7G tRNA methylome is required for normal mRNA translation and embryonic stem cell self-renewal and differentiation. Mol. Cell 71, 244–255.e5 (2018).

    Article 
    CAS 

    Google Scholar 

  • Deng, Y., Zhou, Z., Ji, W., Lin, S. & Wang, M. METTL1-mediated m7G methylation maintains pluripotency in human stem cells and limits mesoderm differentiation and vascular development. Stem Cell Res. Ther. 11, 306 (2020).

    Article 
    CAS 

    Google Scholar 

  • De Bie, L. G. et al. The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase. J. Bacteriol. 185, 3238–3243 (2003).

    Article 

    Google Scholar 

  • Zhou, H. et al. Monomeric tRNA (m7G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion. Proteins 76, 512–515 (2009).

    Article 
    CAS 

    Google Scholar 

  • Leulliot, N. et al. Structure of the yeast tRNA m7G methylation complex. Structure 16, 52–61 (2008).

    Article 
    CAS 

    Google Scholar 

  • Cartlidge, R. A. et al. The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells. EMBO J. 24, 1696–1705 (2005).

    Article 
    CAS 

    Google Scholar 

  • Okamoto, M. et al. tRNA modifying enzymes, NSUN2 and METTL1, determine sensitivity to 5-fluorouracil in HeLa cells. PLoS Genet. 10, e1004639 (2014).

    Article 

    Google Scholar 

  • Benas, P. et al. The crystal structure of HIV reverse-transcription primer tRNA(Lys,3) shows a canonical anticodon loop. RNA 6, 1347–1355 (2000).

    Article 
    CAS 

    Google Scholar 

  • Bou-Nader, C. et al. HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization. Cell Host Microbe 29, 1421–1436.e7 (2021).

    Article 
    CAS 

    Google Scholar 

  • Finer-Moore, J., Czudnochowski, N., O’Connell, J. D. 3rd, Wang, A. L. & Stroud, R. M. Crystal structure of the human tRNA m1A58 methyltransferase-tRNA3Lys complex: refolding of substrate tRNA allows access to the methylation target. J. Mol. Biol. 427, 3862–3876 (2015).

    Article 
    CAS 

    Google Scholar 

  • Blersch, K. F. et al. Structural model of the M7G46 methyltransferase TrmB in complex with tRNA. RNA Biol 18, 2466–2479 (2021).

    Article 
    CAS 

    Google Scholar 

  • Matsumoto, K. et al. RNA recognition mechanism of eukaryote tRNA (m7G46) methyltransferase (Trm8–Trm82 complex). FEBS Lett. 581, 1599–1604 (2007).

    Article 
    CAS 

    Google Scholar 

  • Schultz, S. K. & Kothe, U. tRNA elbow modifications affect the tRNA pseudouridine synthase TruB and the methyltransferase TrmA. RNA 26, 1131–1142 (2020).

    Article 
    CAS 

    Google Scholar 

  • Akimov, V. et al. UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites. Nat. Struct. Mol. Biol. 25, 631–640 (2018).

    Article 
    CAS 

    Google Scholar 

  • Studier, F. W. Protein production by auto-induction in high density shaking cultures. Protein Expr. Purif. 41, 207–234 (2005).

    Article 
    CAS 

    Google Scholar 

  • Minor, W., Cymborowski, M., Otwinowski, Z. & Chruszcz, M. HKL-3000: the integration of data reduction and structure solution—from diffraction images to an initial model in minutes. Acta Crystallogr. D Biol. Crystallogr. 62, 859–866 (2006).

    Article 

    Google Scholar 

  • McCoy, A. J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658–674 (2007).

    Article 
    CAS 

    Google Scholar 

  • Emsley, P. & Cowtan, K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D Biol. Crystallogr. 60, 2126–2132 (2004).

    Article 

    Google Scholar 

  • Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D Biol. Crystallogr. 66, 213–221 (2010).

    Article 
    CAS 

    Google Scholar 

  • Petrov, A., Wu, T., Puglisi, E. V. & Puglisi, J. D. RNA purification by preparative polyacrylamide gel electrophoresis. Methods Enzymol. 530, 315–330 (2013).

    Article 
    CAS 

    Google Scholar 

  • Mastronarde, D. N. Automated electron microscope tomography using robust prediction of specimen movements. J. Struct. Biol. 152, 36–51 (2005).

    Article 

    Google Scholar 

  • Punjani, A., Rubinstein, J. L., Fleet, D. J. & Brubaker, M. A. cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination. Nat. Methods 14, 290–296 (2017).

    Article 
    CAS 

    Google Scholar 

  • Bepler, T. et al. Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs. Nat. Methods 16, 1153–1160 (2019).

    Article 
    CAS 

    Google Scholar 

  • Pettersen, E. F. et al. UCSF ChimeraX: structure visualization for researchers, educators, and developers. Protein Sci. 30, 70–82 (2021).

    Article 
    CAS 

    Google Scholar 

  • Murshudov, G. N. et al. REFMAC5 for the refinement of macromolecular crystal structures. Acta Crystallogr. D Biol. Crystallogr. 67, 355–367 (2011).

    Article 
    CAS 

    Google Scholar 

  • Sievers, F. et al. Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol. Syst. Biol. 7, 539 (2011).

    Article 

    Google Scholar 



  • Source link

    By AUTHOR

    Leave a Reply

    Your email address will not be published. Required fields are marked *