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I disagree that medicine is plagued by untrustworthy clinical trials, and particularly object to the view that you quote: “If you search for all randomized trials on a topic, about a third of the trials will be fabricated” (Nature 619, 454–458; 2023). That opinion is not backed by independently verified data, so I find this reporting sensationalistic and potentially offensive to medical authors.

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The author declares no competing interests.

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